Line of Therapy
Inferred from pharmacy/treatment claims. Tracks initiation, add-on, switch, discontinuation, rechallenge, escalation, and combination events across SM-directed therapy classes.
Patients on therapy
1,450
Median time on therapy
330d
Discontinuation rate
30%
Escalation rate
4%
Combination therapy
49%
AdvSM without TKI
73
15 fully untreated
LoT waterfall
Patients reaching each line of therapy
LoT events
Total events across cohort
Therapy class usage
Unique patients ever exposed to each class
Treatment journey timeline
Pick a treated patient
Select a treated patient to render their LoT episodes, add-ons, switches, and escalation events.